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The top 3 ingredients to avoid in dog food

Learn which harmful preservatives and artificial dyes to spot on labels to help protect your dog at mealtime.

By Rose A. .

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golden Retriever covering his eyes

BHA, BHT(preservative)

  •  Report on Carcinogens, 14th Edition; U.S. Department of Health and Human Services, Public Health Service, National Toxicology Program, CAS No. 25013-16-5, “Carcinogenicity”. 
  • Report on Carcinogens, 14th Edition; U.S. Department of Health and Human Services, Public Health Service, National Toxicology Program, CAS No. 25013-16-5, “Cancer Studies in Experimental Animals” 
  • Common dog food brands that contain this ingredient:
    • Cesar dry and wet dog foods
    • Showtime dog food 
    • Pedigree
    • Kibbles 'n Bits 
    • Purina
  1. Ethoxyquin 
  • Scientific research behind Ethoxyquin
  • Błaszczyk, Alina, Augustyniak, Aleksandra, Skolimowski, Janusz, Ethoxyquin: An Antioxidant Used in Animal Feed, International Journal of Food Science, 2013, 585931, 12 pages, 2013. https://doi.org/10.1155/2013/585931 
  • Egloff S, Pietsch C (2018) Ethoxyquin: a feed additive that poses a risk for aquatic life. Dis Aquat Org 131:39-48 https://doi.org/10.3354/dao03279 
  • Why it is hard to regulate, it enters the supply chain indirectly, has ambiguous and outdated labeling rules, and has a safety threshold that regulators recommended lowering but that regulators never legally enforced. 
  • Solution: human grade dog food, or dog food that avoids fish ingredients 
  1. Food dyes(red 20, blue 2, yellow 5 and 6)
  • Scientific research behind food dyes 
  • Zhang Q, Chumanevich AA, Nguyen I, Chumanevich AA, Sartawi N, Hogan J, Khazan M, Harris Q, Massey B, Chatzistamou I, Buckhaults PJ, Banister CE, Wirth M, Hebert JR, Murphy EA, Hofseth LJ. The synthetic food dye Red 40 causes DNA damage, colonic inflammation, and impacts the microbiome in mice. Toxicol Rep. 2023 Sep 6;11:221-232. doi: 10.1016/j.toxrep.2023.08.006. PMID: 37719200; PMCID: PMC10502305. 
  • Kobylewski, S., & Jacobson, M. F. (2012). Toxicology of food dyes. International Journal of Occupational and Environmental Health, 18(3), 220–246. https://doi.org/10.1179/1077352512Z.00000000034 
  • Common dog food brands that contain this ingredient:
    • Alpo 
    • Pedigree
    • Purina
    • Gravy Train 
    • Rachel Ray Nutrish


Rose A.

Rose A. brings a background in animal biology to everything she writes. She cares about standards. Real ones, the kind that hold up when you look closely at what goes into a product or a pet's daily routine. Her work focuses on quality and the science behind it, translated into plain language that pet owners can actually use. When she isn't digging into research, she's at home with her own dog. He keeps her grounded in what matters most.

This content is for educational and informational purposes only and is not veterinary or professional advice. Eva is not responsible for any loss, injury, or risk arising from reliance on the information here. Eva may earn a commission from affiliate links on this page.

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